Investigated the role of PEMF to control biofilm accumulation and modulate its microbial composition using polymicrobial models that considered a human microbiome.
This represents a breakthrough in prevention effect of peri implant diseases and effect on implant longevity.
Lower levels of P. Gingivalis and pathogen T. Forsythia, – both have been linked to peri-implant tissue destruction were reduced by PEMF.
25 or more bacterial species were reduced by PEMF – shows a potent modulatory effect driven towards a health associated microbial profile.
Electrostatic forces are responsible for mediating bacterial-bacterial interactions and surface attachment, hence responsible for the results seen in this study.
enhances clinical outcomes in peri-implantitis treatment compared to standard care.
Key benefits include:
• Complete plaque elimination
• Substantial reduction in probing depth and bleeding
• Elimination of infection
• Stabilization or regeneration of bone
• Higher overall success rate
The results support the integration of PEMF technology as a therapeutic adjunct in the
management of peri-implant diseases, particularly in difficult or refractory cases.
The PEMF group achieved complete plaque elimination, a 75% reduction in bleeding on probing, and a 2.7 mm reduction in pocket depth. Unlike the control group, which showed bone loss, the PEMF group maintained or gained bone. Overall treatment success was 71.4%, compared to 50% in the control group – a ~40% improvement.
A prospective double blind randomized controlled trial that examined Pulsed Electromagnetic Field in treatment of peri-implantitis on patients that were treated with dental implants and crowns a few years ago
One month after treating with MED, we saw a reduction of marginal bone loss which remains constant after 3 months follow-up
Randomized controlled clinical trial on 40 implants placed in 20 patients
Implant stability change from baseline in ISQ (Implant Stability Quotient)
PEMF not only reduces the inflammatory activity of macrophages and the degradative activity of osteoclasts but that the EVS produced by macrophages, obtained from PEMF treatment, positively affect osteoclasts by reducing their activity.
This finding underscores the crucial role of EVs-mediated signaling in modulating osteoclastogenesis and highlights the potential for EVs to influence bone remodeling by maintaining a delicate balance between bone formation and resorption.
Left Image: SEM Analyses of THP-I
(A, B) in normal conditions, Round morphology M1 phenotype typical.
(C, D) with PEMF, acquire a Fusiform morphology M2 phenotype typical.
Controlled preclinical study on New Zealand rabbit tibia with micro-CT and histology
Antimicrobial effects of a pulsed electromagnetic field: an in vitro polymicrobial periodontal subgingival biofilm model
Changes in bacterial biofilm around implant
Miniaturized Electromagnetic Device Abutment Improves Stability of Dental Implants
The study showcases the promising applications of PEMFs in advancing patient care and treatment methodologies.
PEMFs have been widely used to enhance bone repair, accelerating healing process of recent fracture by promoting the callus formation, which can be achieved through four distinct phases: inflammatory, angio-mesenchymal, bone formation, and remodeling phases.
Novel biophysical approaches that promote oral tissue healing offer various advantages due to their nonconsumable nature, ease of access to oral wounds, and efficacy of promoting the endogenous healing process that would reduce frequent patient visits and reduce the cost of overall therapy.