Clinical Research

Published on: 30 May 2025

PEMF Shows Clinical Success in Peri-Implantitis Treatment: Enhancing Bone Defect Fill and Lowering IL-1β Levels Without Adjunctive Antibiotics.

PEMF therapy has demonstrated clinical benefits in peri-implantitis treatment, promoting significant bone defect fill and reducing IL-1β levels. This non-surgical approach eliminates the need for adjunctive antibiotics while effectively addressing infection, inflammation, and bone healing in a single therapy.

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Published on: 26 February 2025

Microbiome Modulation of Implant-Related Infection by a Novel Miniaturized Pulsed Electromagnetic Field Device

A novel miniaturized PEMF device has been shown to modulate the implant-related microbiome and control biofilm accumulation. The therapy reduces harmful pathogens such as P. gingivalis and T. forsythia, which are linked to peri-implant tissue destruction.

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Published on: 2 Aug 2025

PEMF Therapy on Nonsurgical Treatment of Peri-Implantitis: 12-26 Months Follow-Up

PEMF therapy, known for immunomodulatory effects, reduces soft tissue inflammation and marginal bone loss. This retrospective-prospective analysis compared long-term outcomes with and without PEMF therapy.

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Published on: 18 July 2023

Bone Growth in Inflammatory Condition: Peri-implantitis Clinical Trial

A prospective, double-blind randomized clinical trial evaluated PEMF therapy for peri-implantitis in patients with dental implants and crowns. Treatment with Magdent’s MED device resulted in a notable reduction in marginal bone loss after one month. This improvement remained stable during a three-month follow-up.

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Published on: 3 April 2020

Accelerated Osseointegration: Effect of the Pulsed Electromagnetic Field (PEMF) on Dental Implants Stability, A Randomized Controlled Clinical Trial

A randomized controlled clinical trial assessed the effect of PEMF on the stability of 40 dental implants in 20 patients. The test group showed a significant 13% increase in implant stability, compared to a 2% decrease in the control group.

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Published on: 24 Aug 2024

Bone Regeneration Revolution: Pulsed Electromagnetic Field Modulates Macrophage-Derived Exosomes to Attenuate Osteoclastogenesis

PEMF therapy reduces inflammatory activity in macrophages and decreases osteoclast degradative activity. Extracellular vesicles (EVs) produced by PEMF-treated macrophages further suppress osteoclast activity. This highlights the key role of EV-mediated signaling in regulating osteoclastogenesis.

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Published on: 13 June 2015

A new device for improving dental implants anchorage: a histological and micro-computed tomography study in the rabbit

A controlled preclinical study on New Zealand rabbit tibia evaluated a new device for improving dental implant anchorage. Micro-CT and histological analysis showed a 48% increase in bone-to-implant contact and a 62% rise in trabecular bone volume density.

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Published on: 29 Sep 2020

Antimicrobial effects of a pulsed electromagnetic field: an in vitro polymicrobial periodontal subgingival biofilm model

A controlled in-vitro study investigated the effect of PEMF on bacterial colonization around dental implants. Using a polymicrobial subgingival biofilm model, PEMF significantly reduced total bacterial counts compared to the control group.

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Published on: 30 Jun 2019

Miniaturized Electromagnetic Device Abutment Improves Stability of the Dental Implants

A retrospective controlled clinical trial evaluated the effect of PEMF on 24 implants in 12 patients. The miniaturized electromagnetic device abutment significantly improved implant stability compared to controls.

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Published on: 23 March 2018

Pulsed electromagnetic fields increase osteogenetic commitment of MSCs via the mTOR pathway in TNF-α mediated inflammatory conditions: an in-vitro study

A controlled in-vitro study evaluated the effect of PEMF on osteoblast formation under normal and inflammatory conditions. PEMF enhanced MSC differentiation into osteoblasts, even in TNF-α–mediated inflammation.

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Published on: 9 July 2021

Pulsed Electromagnetic Fields in Bone Healing: Molecular Pathways and Clinical Applications

Recent literature highlights the clinical applications of PEMFs in bone healing. PEMF therapy accelerates fracture repair by promoting callus formation across inflammatory, angio-mesenchymal, bone formation, and remodeling phases.

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Published on: 13 Aug 2022

PEMF Is a Noninvasive Therapeutic Form of Low Field Magnetic Stimulation for Bone Healing

PEMF is a noninvasive therapy using low-field magnetic stimulation to promote healing of bone non-unions and fractures. As an adjunct to implant osseointegration, it enhances oral tissue regeneration.

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